Autoimmunity Link in Long COVID Patients
Researchers identified autoantibodies as a driver of long COVID symptoms in a subset of individuals, suggesting new treatment pathways.
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Autoimmunity Link in Long COVID Patients
Researchers identified autoantibodies as a driver of long COVID symptoms in a subset of individuals, suggesting new treatment pathways.
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Microplastics May Intensify Immune Response to Common Allergens
New research suggests that microplastic particles can bind to allergens and carry them deeper into the respiratory system.
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Inhaled Molgramostim Improved Exercise Capacity
Phase 3 clinical trial data shows improvements in walking distance and duration for patients with autoimmune pulmonary alveolar proteinosis treated with inhaled molgramostim.
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Infant Immune Response May Explain RSV Severity Compared to SARS-CoV-2
A study found that infant immune systems respond very differently to RSV and SARS-CoV-2, with important treatment implications.
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Reevaluating Salt Intake for Cystic Fibrosis Patients
Researchers assessed salt intake in cystic fibrosis patients undergoing treatment with CFTR modulators, which improve salt conservation and other physiological markers.
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New Standard of Care Recommended for Recurrent Respiratory Papillomatosis
Papzimeos (zopapogene imadenovec) is recommended as the new first-line treatment for adults with recurrent respiratory papillomatosis (RRP), which affects an estimated 27,000 US adults.
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Positive Data for Low-dose Peanut Oral Immunotherapy
A 30 mg peanut oral immunotherapy maintenance dose improved peanut tolerance to a similar extent as a higher 300 mg dose, while being associated with fewer systemic adverse events.
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Circadian Rhythms Help Boost Flu Recovery
Circadian rhythms of the host are a critical determinant of outcomes and may be modified by well-timed environmental cues with potential to drive outcomes in severe flu infection.
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Link Between Pediatric Eczema Patterns, Ability to Outgrow Food Allergies
Eczema is more than just a coexisting condition—it may directly influence whether children overcome food allergies.
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Effects of Oral Immunotherapy, Oral Food Challenges on Pediatric Outcomes, Outlook
Oral immunotherapy and oral food challenges (OFCs) are both safe for young patients and can be life-changing for families navigating food allergies.
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New COPD Subtype Discovered
Researchers used machine learning to identify a unique new subtype of COPD: the emphysema inflammatory subgroup (EIS), which differs from other COPD subtypes in its immune profile and a more distinctive form of emphysema.
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Exercise Rehab Aids Immune System in Long COVID Patients
An eight-week exercise-based rehabilitation program improved immune function in patients with long COVID.
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Lung Cancer Rewires Immune Cells in Bone Marrow
Tumors rewire immune cells in the bone marrow before they even reach the cancer, suggesting a new target to enhance the durability of current immunotherapy.
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Immunotherapy Plus Chemotherapy Before Lung Cancer Surgery Significantly Improves Long-term Survival
Adding immunotherapy (nivolumab) to chemotherapy before surgery significantly improved long-term overall survival for patients with operable non-small cell lung cancer (NSCLC) compared to chemotherapy alone.
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How Infant Immune Systems Respond to Severe COVID-19
Infants hospitalized with severe COVID-19 have significantly different immune responses than adults or older children, according to research published in Nature Communications.
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SARS-CoV-2 Corrupts White Blood Cells, Suppresses Immune System
SARS-CoV-2, the virus that causes COVID-19, can “reprogram” pathogen-fighting white blood cells known as neutrophils into immune system suppressing cells known as PMN-MDSCs.
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Inhaled Microplastics Inhibit Key Immune Cell in the Lungs
Microplastics suppress pulmonary macrophages, a type of white blood cell found in the lungs that are critical to the immune system.
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Immune Cell Networks Drive Pulmonary Fibrosis
Networks of misplaced immune cells drive idiopathic pulmonary fibrosis — a discovery that may create a pathway to new treatments.
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Investigational Asthma Treatment Targets Key Molecules
Two potential asthma treatments that target key molecules to prevent immune cells from triggering asthma attacks, offering the possibility of long-term relief.
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New Guidance Seeks to Ease Documentation Hurdles for Allergy Shot Claims
Recommendations from ACAAI, AAAAI, and AAOA aim to simplify documentation requirements for allergen immunotherapy claims to prevent undue burden on healthcare providers and ensure timely patient access.
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FDA Approves Durvalumab-Chemo Combo for Resectable NSCLC
The approval was based on trial results which showed the regimen reduced the risk of recurrence, progression, or death by 32% versus neoadjuvant chemotherapy alone.
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NIH Grant Funds Research into Neutrophils’ Role in Lung Health
The $12 million NIH grant will fund research on how lung neutrophils contribute to injury, inflammation, and repair in severe respiratory conditions.
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AI-Powered Immunotherapy Ends Milk Allergy Restrictions for Kids
The Food Allergy Institute’s study shows that 100% of participants achieved milk allergy remission, with results maintained for at least a year.
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Anti-Inflammatory Approach Succeeds in Lung Cancer Trial
The novel approach has yielded a 67% overall response rate in a small clinical trial for patients with advanced non-small cell lung cancer.
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