FDA Greenlights Phase 2 Study of Inhaled mRNA Treatment for Cystic Fibrosis
The phase 2 study will evaluate the safety and efficacy of ARCT-032, an inhaled mRNA therapy for cystic fibrosis patients, which previously received Orphan Drug Designation.
Category: Cystic fibrosis
Cystic fibrosis
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Cystic fibrosis
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Jumbo Phage Identified with Potential to Combat CF Lung Infections
Researchers in the United Kingdom have isolated a jumbo phage from wastewater with the potential to fight lung infections caused by Burkholderia cenocepacia.
Cystic fibrosis
LatestHealth Canada OKs Trikafta for Younger Children With Cystic Fibrosis
Health Canada granted market authorization for the expanded use of Trikafta to include children with cystic fibrosis ages 2-5 years who have at least one copy of the F508del mutation in the CFTR gene.
Delayed Cystic Fibrosis Care Tied to Poorer Long-term Nutritional Outcomes
A new study published in The Journal of Pediatrics underscores the importance of timely newborn screenings in early care for cystic fibrosis.
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Inogen Acquires Physio-Assist, Adding Airway Clearance Device to Portfolio
Physio-Assist developed and manufactures Simeox, a technology-enabled airway clearance device currently used outside of the United States to treat bronchiectasis.
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Triple Combination Therapy Effective Long-term for Cystic Fibrosis Patients
Combination therapy involving three drugs—elexacaftor, tezacaftor, and ivacaftor—can achieve positive, lasting effects in patients with cystic fibrosis, according to new research evaluating the therapy over 12 months.
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European Commission Approves Earlier Use of Cystic Fibrosis Drug Orkambi
Nearly 300 children with cystic fibrosis and two copies of the F508del mutation are now eligible for the first time for a medicine that can treat the underlying cause of their disease.
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FDA Approves Manufacturing Site for C. difficile Preventative Therapy
Recipharm’s Vowst therapy is approved to prevent reinfection of C. difficile, which can infect patients with cystic fibrosis and other chronic diseases.
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FDA Grants Kalydeco Expanded Approval for Infants with Cystic Fibrosis
The medication now is approved for use in children with cystic fibrosis ages 1 month to less than 4 months old who have at least one mutation in their cystic fibrosis transmembrane conductance regulator gene.Â
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Positive Data from Phase 1b/2a Study of Pulmonary Infection Treatment
BiomX has announced positive data from a study assessing the safety and tolerability of BX004 in nine cystic patients.
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Comparing Airway Clearance Therapies
Researchers compared airway clearance interventions in cystic fibrosis patients using specific cough technique (SCT) and forced expiration technique (FET). Â
Read MoreCystic Fibrosis Drug Could Help Treat Pneumonia
A cystic fibrosis drug proves effective, raising hope that it could be used to treat pneumonia regardless of the pathogen that caused it.
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Airway Protein May Be Key to Body’s Mucociliary Clearance
MUC5AC, an airway protein, plays an important (and overlooked) role in the body’s mucociliary clearance system, according to research published in Science Advances.
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Vaping Nicotine Impairs Airway Clearance
Vaping with nicotine impairs ciliary beat frequency, dehydrates airway fluid and makes mucus more viscous or sticky, new research has found.
Read MoreHow a Cystic Fibrosis Urine Test Can Help Monitor Patients
A newly-developed cystic fibrosis urine test can make it much easier for doctors to diagnose how badly a patient is affected by the hereditary diseases.
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