Moderna Withdraws FDA Application for Combo Flu-COVID Vaccine
Moderna's biologics license application for its flu/COVID combination vaccine candidate for adults aged 50 years and older.
Category: Influenza
Influenza
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Moderna Withdraws FDA Application for Combo Flu-COVID Vaccine
Moderna’s biologics license application for its flu/COVID combination vaccine candidate for adults aged 50 years and older.
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Hospitalization for Sepsis, Respiratory Infections Linked to Heart Failure Risks
Adults who were hospitalized for a severe infection, such as respiratory infections or sepsis, were more than twice as likely to develop heart failure years later.
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Bird Flu Is Infecting Cats—What Are the Risks?
H5N1 avian flu has been detected in domestic cats across the United States. Are there risks of cat-to-human transmission?
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CDC: ‘The Decision to Vaccinate Is a Personal One’
A recent CDC statement may signal a shift in the agency’s longstanding practice of advocating vaccinations for infectious diseases like measles.
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H5N1 Avian Flu Mutating to Infiltrate Human Cells
Existing H5N1 avian flu vaccines may be less effective against newer strains due to rapid viral adaptation.
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Current Antivirals Less Effective Against Severe Bird Flu
Two FDA–approved flu antivirals did not successfully treat severe H5N1 infections, and route of infection (eye, nose or mouth) significantly impacted effectiveness.
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FDA Issues Recommendations for Flu Vaccine Composition
The FDA convened an interagency panel to comprise its recommendations for the 2025-2026 flu vaccine composition.
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Parents Want Accurate Info on Bird Flu
A national poll found 2-in-5 parents wish the government was doing more to prevent a bird flu outbreak.
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Biosensor Can Detect Airborne Bird Flu in Under Five Minutes
A portable biosensor cuts detection time for airborne H5N1 virus particles to less than five minutes — significantly faster than conventional PCR tests.
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FDA, CDC Cancel Flu Vaccine Advisory Meetings
A scheduled meeting of the US FDA’s influenza vaccine advisory board set for March 13 has been canceled, following another postponement by the CDC last week.
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FDA Clears Visby Medical Flu + COVID Test
Visby Medical’s handheld PCR test that differentiates between influenza A, B, and COVID-19 received FDA clearance and a CLIA waiver.
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Acetaminophen Overdoses Reported in Flu Patients
Cold and flu season is the time of year when Poison Control Centers see an increase in calls related to the overuse of acetaminophen to alleviate flu-like symptoms.
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Influenza A Viruses Can Adapt Shape
Influenza A viruses rapidly adjust their shape when placed in conditions that reduce infection efficiency, such as the presence of antiviral antibodies or host incompatibility.
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Single Dose of Broadly Neutralizing Antibody Protects Macaques from H5N1 Influenza
National Institutes of Health (NIH) scientists and their colleagues report that a single dose of a broadly neutralizing antibody (bnAb) administered prior to virus exposure protects macaques from severe H5N1 avian influenza.
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New Approach for Antiviral Development
A new antiviral modeling approach combines various experimental techniques to create a comprehensive picture of a virus’ dynamic behavior.
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CDC: Highest Influenza Activity in 15 Years
According to a CDC update, as of February 1, 2025, influenza test positivity increased to 31.6% nationally.
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Experimental Vaccine Protects Mice Against Bird Flu Circulating in Cattle
The RNA-based vaccine showed full protection in mice against the H5N1 strain circulating in US cattle.
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H5N1-Contaminated Milk May Pose Lower Risk Than Respiratory Exposure
Monkeys exposed to H5N1 via the mouth and stomach resulted in limited infection without clinical signs, while exposure via the nose and windpipe caused mild to severe illness.
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Louisiana Reports First US H5N1 Bird Flu Death
A Louisiana patient over the age of 65 has died after contracting H5N1 bird flu from exposure to wild and backyard birds.
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Four Keys to Controlling the Bird Flu Outbreak
National Institutes of Health officials have outlined four strategies for managing the H5N1 avian influenza outbreak.
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California Declares State of Emergency for Bird Flu Response
California Governor Gavin Newsom declared a State of Emergency to strengthen the state’s response to bird flu after its detection in Southern California dairy cows and its spread to 16 states.
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Louisiana Patient Hospitalized With Severe H5N1 Bird Flu
A patient in Louisiana has been hospitalized with a severe case of H5N1 bird flu, marking the first instance of severe illness linked to the virus in the United States, according to the CDC.
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Unexpected Flu Defense Found in Pregnancy
Researchers discovered that pregnancy strengthens immune defenses, contrary to common belief, blocking the flu virus from spreading to the lungs.
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Bird Flu Mutation Could Increase Human Transmission Risk
An NIH-funded study identified a mutation in the H5N1 avian influenza virus that enhances its ability to bind to human cells.
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