Genetic Risk for COPD Linked to Lower Lung Function from Childhood
A new study finds individuals with higher genetic risk for COPD show lower lung function starting in childhood.
Tag: genetics
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Why COVID-19 Spares Some and Strikes Others
In a new study, Cedars-Sinai investigators explore what factors increase susceptibility to COVID-19.
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Smoking Hastens Aging, Study Finds
Researchers found that smoking significantly shortens telomeres—indicators of aging and cellular repair capability—and the more cigarettes consumed, the greater the shortening effect.
Gene on Y Chromosome Protects Against Pulmonary Hypertension
A gene on the Y chromosome protects against pulmonary hypertension, which may partially explain why the disease occurs four times more often in women than men.
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Genetics May Play a Role in Managing Stress of COVID-19 Pandemic
Some individuals managed the stress of the COVID-19 pandemic better than others, in part, due to their genetics, according to a new study published in Plos Genetics.
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Tuberculosis Strains Attack Body Differently
Two tuberculosis strains have only minor genetic differences but attack the lungs in completely different fashion.
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Gene Variant Indicates Effectiveness of Immunotherapy for Allergies
Results suggest that allergy patients carrying a genetic variant have an increased risk of being non-responders to sublingual immunotherapy in their second season of the immunotherapy.
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Study: Lung Function in Pediatric Cystic Fibrosis Patients Different in US vs UK
Pediatric patients with cystic fibrosis with the homozygous F508del genotype in the U.S. had better lung function than children in the U.K., data published in Thorax shows.
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COPD: Altered Gene Expression and Cell Interactions
Researchers have identified altered gene expression and cellular interactions between epithelial, endothelial, and macrophage cells in the lungs of COPD patients.
Read MoreSilencing This Faulty ALS Gene May Uncover Clues to Rare Forms
An experimental drug suppressed a mutated amyotrophic lateral sclerosis gene, offering a potential therapy for rare, aggressive forms of ALS caused by mutations in the fused in sarcoma (FUS) gene.
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Damaged Telomeres in Seniors May Increase Susceptibility to SARS-CoV-2
Age-related telomere shortening or dysfunction may be a molecular explanation for the increased sensitivity of elderly people to SARS-CoV.
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Genetic Differences in Immune Responses
New research found differences in immune pathway activation to influenza infection between individuals of European and African genetic ancestry.
Read MoreCytokine Levels Could Predict Asthma Patients’ Response to Benralizumab
Levels of inflammatory cytokines in patients with severe asthma may predict responses to the monoclonal antibody benralizumab, a study in the Journal of Asthma suggests.
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A New Pathway to Suppress The Cystic Fibrosis Mutation
A new treatment approach could pave the way to innovative new gene therapies for cystic fibrosis.
Read MoreStudy Underway to Use Personalized Medicine to Treat Asthma
A new phase 2 clinical trial of multiple therapies to treat patients with severe asthma, specifically focusing on personalized therapies based on genetics, family history, lifestyle and environmental factors, is currently underway.
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