Category: Chronic Pulmonary Disorders

Chronic Pulmonary Disorders

Comorbid Bronchiectasis + Diabetes Tied to Worse Outcomes

A large-scale international study found that comorbid bronchiectasis and diabetes is associated with higher mortality, increased hospitalizations, and more frequent exacerbations.

Chronic Pulmonary Disorders

Pediatric Interstitial Lung Disease Tied to Novel Disorder with Genetic Causes

Researchers linked loss-of-function variants in the TMEM63B gene to a novel disorder causing interstitial lung disease in some pediatric patients.

Chronic Pulmonary Disorders

Microplastics May Intensify Immune Response to Common Allergens

New research suggests that microplastic particles can bind to allergens and carry them deeper into the respiratory system.

Asthma

Tezepelumab Reduced Asthma Attacks

A new study shows tezepelumab (Tezspire) reduced asthma exacerbations by 70% across all patient subgroups, including smokers and those with comorbid conditions.

COPD

Why Some Alpha-1 Patients Develop Liver Disease

A newly discovered biological process protects liver cells from protein buildup in patients with alpha-1-antitrypsin deficiency.

Cystic fibrosis

COVID-19 Outcomes in Cystic Fibrosis Transplant Patients

New research indicates that baseline lung health is a stronger predictor of SARS-CoV-2 outcomes in cystic fibrosis transplantation patients than the time elapsed since transplantation.

Pulmonary Fibrosis

New Data on Inhaled Treprostinil for IPF

Data from clinical trials investigating treatments for pulmonary hypertension and pulmonary fibrosis will be highlighted at ATS 2026.

Allergies

Fatal Pediatric Anaphylaxis Linked to Delays in Epinephrine Treatment

New studies suggest that airway and breathing failures are the primary causes of death in childhood food anaphylaxis, requiring a shift in emergency management protocols.

Other Chronic Diseases

Alpha-1 Drug Candidate Superior to Standard Care

Phase 2 data for efdoralprin alfa demonstrate the recombinant protein maintains normal protein levels with less frequent dosing than current standards of care for patients with alpha-1 antitrypsin deficiency (AATD)-related emphysema.