According to a study in Clinical Infectious Disease, the flu vaccine was effective at reducing the risk for flu-related hospitalizations in pregnant women.

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Among 19,450 hospitalizations with an acute respiratory or febrile illness (ARFI) discharge diagnosis, only 6% (1,030) of the pregnant women were tested for influenza viruses using real-time reverse transcription polymerase chain reaction.

Of these women, approximately half had pneumonia or influenza discharge diagnoses (54%), with influenza A or B virus infection detection in 598 of 1,030 (58%) of the ARFI hospitalizations. Adjusted overall influenza vaccine effectiveness was 40% against influenza-associated hospitalization during pregnancy.