Abdominal muscle activity during mechanically ventilation is one of the injurious factors in severe acute respiratory distress syndrome (ARDS) and abdominal muscle paralysis might be an effective strategy to minimize ventilator-induced lung injury, according to research in Plos One.

No previous studies have proved the relationships between abdominal muscle and ventilator-associated lung injury in ARDS, researchers wrote. In an oleic acid-induced ARDS model of male beagles, the study showed that BIPAPAP (abdominal muscle paralysis) had lower mRNA expression of interleukin-6 and IL-8 in lung tissues and less total cumulative histopathological lung injury scores compared with BIPAPSB (spontaneous breathing) group.

These findings suggested that activity of the abdominal muscle during mechanically ventilation was one of the injurious factors in severe ARDS.

Read more at journals.plos.org