A study published in the American Journal of Respiratory and Critical Care Medicine investigated how increased vigorous exercise in cystic fibrosis patients affected lung function for sedentary patients with cystic fibrosis.

Researchers found that increased vigorous exercise in cystic fibrosis did not result in improved FEV1 at 6 months. In fact, those CF patients who did not change their physical activity had a higher FEV1 after 6 months.

“Changing physical activity behavior in the general population or people with cystic fibrosis is difficult due to a plethora of perceived barriers, such as lack of time, tiredness, stigma and demoralization. In general, a multicomponent intervention has the potential to elicit beneficial effects,” Helge Hebestreit, MDprofessor in the pediatric department at the University Hospitals Würzburg, Germany, and colleagues wrote.

“There is evidence that motivational interviewing, counseling, a written activity plan and regular feedback from pedometers or diaries are beneficial.”

ACTIVATE-CF, an international, parallel-arm, multicenter, randomized controlled trial, enrolled 117 relatively inactive patients aged 12 years and older with cystic fibrosis. All patients were randomly assigned to an intervention group (n = 60; mean age, 25.3 years; 55% female), in which patients added 3 hours of vigorous exercise per week, or the control group (n = 57; mean age, 22.8 years; 56% female), in which patients did not change their physical activity behavior.

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vigorous exercise in cystic fibrosis

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exercise in cystic fibrosis