Heart failure patients who also have COPD have a greater mortality risk than heart failure patients without the lung disease, according to a study published in JAMA Network Open.

Researchers performed studies of HF patients, with and without COPD, to assess the associations between COPD medication intensity or stage of airflow limitation, and the risk of hospitalization or death in patients with HF.

This nested case-control study of 50,114 patients with HF (median age 79; 46% women) showed that COPD (18,478 cases or 13.8%) was significantly associated with hospitalization (adjusted odds ratio 1.33, 95% CI, 1.26-1.39) and increased death (aOR 1.31, 95% CI 1.26-1.36).

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