The Babi.Plus system provides noninvasive breathing assistance for premature infants to help reduce the risk of lung disease.


RT’s Three Key Takeaways:

  1. Neonatal Respiratory Support: The Babi.Plus Bubble nCPAP System provides a noninvasive method to deliver heated and humidified airflow to premature infants weighing 10 kg or less.
  2. Clinical Benefits: Use of bubble CPAP is associated with a reduction in the need for intubation and mechanical ventilation, as well as a decrease in bronchopulmonary dysplasia.
  3. System Components: The system includes a FDA-cleared bubble CPAP valve, pressure relief manifold, and silicone nasal cannulas available in eight sizes to ensure stability and accuracy during therapy.


Respiralogics offers the Babi.Plus Bubble nCPAP System, designed to provide a safe and accurate method of delivering continuous positive airway pressure (CPAP) to infants in neonatal critical care units, delivery rooms, and special procedure units.

Respiratory Distress Syndrome in very low birth weight and premature infants is commonly caused by lung immaturity and surfactant deficiency. According to Respiralogics, the use of bubble CPAP has experienced a resurgence due to a reduction in the need for intubation and mechanical ventilation and a reported decrease in bronchopulmonary dysplasia (BPD) from recognized neonatal intensive care unit (NICU) centers of excellence.

Bubble CPAP uses a nasal cannula gas delivery system that terminates beneath the surface of a water reservoir to generate bubbles. This method assists in keeping the infant’s lungs open at end exhalation while allowing for spontaneous breathing.

The Babi.Plus Bubble PAP Valve received market clearance from the FDA in May 2009 for single-patient use in patients weighing 10 kg or less. The valve increases end lung pressure above atmospheric levels in a constant flow condition. The system is designed to eliminate the time-consuming tasks often associated with the assembly and maintenance of hospital-assembled CPAP devices, allowing clinicians to focus on patient care, according to the company.

The Babi.Plus Cannula Kit features contoured nasal prongs made from non-reactive silicone and a unique cannula body to provide stability during therapy. An integrated pressure monitoring line allows for the monitoring of nasal prong pressure without placing lines near the infant’s face. The cannulas are offered in eight different sizes to accommodate a wide range of infants, from premature neonates to infants weighing 10 kg or less.

To ensure safety, the system includes a single-use pressure relief manifold designed to prevent breathing circuit pressure from exceeding preset limits. Additional accessories include the Venti.Plus pole clamps, which are designed to support the bubble PAP valve and a humidifier on a typical equipment pole. The system also includes baby caps, chin straps, and nose bumpers to assist with the delivery of Bubble CPAP in neonatal healthcare environments.

Source

  1. https://respiratory-therapy.com/products-treatment/monitoring-treatment/therapy-devices/products-2025-bubble-cpap/
  2. https://respiralogics.com/content/babi_nCPAP_system.html