Milder Blood Stem Cell Transplants Preserves Lung Function in Sickle Cell Patients
An NIH study found that lung function remained stable or improved after patients with sickle cell disease underwent low-intensity blood stem cell transplants.
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Milder Blood Stem Cell Transplants Preserves Lung Function in Sickle Cell Patients
An NIH study found that lung function remained stable or improved after patients with sickle cell disease underwent low-intensity blood stem cell transplants.
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Scientists Correct Cystic Fibrosis Genes in Mice for Almost Two Years
The scientists developed nanoparticles that successfully edited the disease-causing gene in the lungs of a mouse model of cystic fibrosis.
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Mouse Lungs Successfully Generated in Rats
A combination of CRISPR/Cas9 genome editing and blastocyst complementation was used to produce mouse lungs in rats for the first time.
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New Cell Therapy Reduces Mortality for COVID-19-related ARDS
An initial trial suggests invariant natural killer cell therapy improves survival.
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Model Created to Decode ABCA3 Mutation’s Role in Childhood Lung Disease
Researchers demonstrate how they can now study the most common genetic cause of pediatric interstitial lung disease using stem cells generated from each patient.
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The Quest to Grow Transplant Lungs via Animal Stem Cells
To compensate for a shortage of lung donors for COPD patients, regenerative medicine is making strides in developing lungs from pluripotent stem cells (PSCs), using interspecies animal models.
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Early Lung Development Driven by Immune Cells
The work reveals a “surprising” coordination between the immune and respiratory systems, much earlier in development than previously thought, according to the researchers.
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Transplanting COPD Patients’ Own Cells Restores Lung Function
Researchers have shown it is possible to repair damaged lung tissue in patients with chronic obstructive pulmonary disease using the patients’ own lung cells.
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Disease-causing Stem Cells Dominate Lungs of Advanced CF Patients
Five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis (CF), and these variants drive key aspects of CF pathology including inflammation, fibrosis, and mucin secretion, according to new research.
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Cell Therapy Slashes COVID-19 Death Risk by 60%
Cell therapy has been shown to significantly reduce the mortality risk in COVID-19 patients based on an analysis of nearly 200 clinical trials conducted since 2020.
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Smoking Hastens Aging, Study Finds
Researchers found that smoking significantly shortens telomeres—indicators of aging and cellular repair capability—and the more cigarettes consumed, the greater the shortening effect.
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Therapy Derived from Skin Cells May Be Able to Treat Injured Lungs
The hope is that a drop of solution containing these nanocarriers, delivered to the lungs via the nose, could treat acute respiratory distress syndrome.
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Blocking Receptor Reduces Influenza A Virus’ Ability to Invade Cells
A team from the University of Geneva has identified how the influenza A virus manages to penetrate cells to infect them.
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Variant Cells Discovered in Lungs of IPF Patients
Stem cell cloning experts are reporting their findings of variant cells in the lungs of patients with idiopathic pulmonary fibrosis, which likely represent key targets in any future therapy for the condition.
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Key Protein Responsible for COVID-19 Spread Between Cells Identified
Researchers at the University of Missouri have identified a specific protein inside the human body that plays a critical role in how the virus spreads from cell to cell after infection.
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Overlooked Airway Cell Type Holds Promise for Respiratory Diseases
Researchers discovered a new cell state in embryonic airway development—overlooked until now—that they say may pave the way for new approaches to treating chronic respiratory diseases.
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Study: Restoring the Airways’ Seal in CF
Using a model reproducing a respiratory epithelium, teams from the University of Geneva have discovered that a film of liquid is sufficient to restore the airways’ seal and lower the risk of bacterial infection.
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Infant Nasal Cells Similar to Lung Cells in RNA Patterns
New research from the University of Rochester Medical Center (URMC) reveals that cells from an infant’s nose are similar to those found in the lungs, which is a discovery that may lead to a more precise diagnosis of RSV and other infant lung diseases.
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Increase in Unproven Stem Cell Therapies for Lung Disease
A Boston University School of Medicine report reveals there is an increasing number of clinics around the world offering stem cell-based therapies that are ineffective or have no benefit.
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3B Medical to Support Stem Cell Research
3B Medical will allocate a significant portion of its profits to fund research into proof-of-concept studies in use of adipose derived autologous mesenchymal stem cells.
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How Epithelial Cells Repair Themselves After Chemical Pneumonitis
The repair of injured epithelial cells following exposure to chlorine gas is necessary to restore normal lung structure and function.
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Stem Cell Research: A Brave New World?
Researchers are thrilled about the recently signed executive order that reverses former President Bush’s ban on federally funded embryonic stem cell research.
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