College students who vape have lower cognitive function scores, a study suggests.


RT’s Three Key Takeaways:

  1. Lower Cognitive Function Linked to Vaping: College students who vaped had lower cognitive function scores than their non-vaping peers, with those who vaped more frequently showing a greater decline. Students who both smoked and vaped had the lowest scores overall.
  2. Vaping Frequency Affects Cognitive Performance: The study found a correlation between the number of puffs per day and cognitive impairment. Students who vaped more than 20 puffs a day scored 13.7% lower than non-vapers, while those who vaped 10 to 20 puffs saw a 9.2% decrease.
  3. Nicotine Exposure May Harm Brain Health: Despite being promoted as a safer alternative to smoking, vaping was associated with significant nicotine exposure, which the study suggests could damage brain cells and reduce blood flow to the brain, impacting cognitive function.

College students who vaped had lower cognitive function scores than those who didn’t, and the more they vaped, the bigger the disparity, according to research being presented at the 149th Annual Meeting of the American Neurological Association (ANA).

The study also found college students who vaped and smoked had the lowest scores. While using electronic cigarettes (vaping) has been shown to cause lung damage, the research presented at ANA is different because there is little to no information on vaping’s relationship to cognitive function, such as learning, memory, problem-solving, critical thinking, and decision-making. Cognitive testing is rarely performed in young people.

“People in the study who had previously smoked cigarettes typically smoked three or four a week, but with vaping, they now smoke double, triple, or more, especially if they smoke and vape,” says Linker Viñan Paucar, lead author of the study and a final-year medical student at Catholic University of Santiago de Guayaquil, Ecuador, in a release. “Electronic cigarettes with up to 20,000 puffs are supposed to last three months, but we found many students finished them before the first month and started using others.”

The study included 405 Hispanic college students ages 18-30 who attended one of two universities in Guayaquil, Ecuador: 64 only vaped; 31 only smoked cigarettes; 111 smoked and vaped; and 199 never smoked or vaped. All were given Montreal Cognitive Assessment (MoCA) tests, for which scores 26 and above are considered normal and those below 25 may indicate some cognitive impairment. MoCA scores were as follows. 

Students who:

  • Did not smoke or vape scored a median of 26 (low of 18)
  • Only vaped scored a median of 24 (low of 16)
  • Only smoked cigarettes scored a median of 25 (low of 22)
  • Vaped and smoking together scored a median of 24 (low of 8)

Researchers also determined students who vaped 10 to 20 puffs per day had scores 9.2% lower than those who did not vape or smoke, and those who vaped more than 20 puffs a day had scores 13.7% lower than those who didn’t vape or smoke.

Effects on Cognition

Initially promoted as a safe alternative to cigarettes, vapes actually contain significant levels of nicotine, Viñan Paucar notes in a release. 

“We believe our research marks a before and after in the field of studying cognitive function regarding vaping,” he says. “It will be important to study vaping in other college students, including those who are Black, white or Asian and Pacific islander.”

Research has shown smoking can affect cognition by reducing brain volume and narrowing the blood vessels, lowering blood flow and oxygen to the brain. Further, nicotine can cause neurotoxicity that damages brain cells.

In 2021, 4.5% of US adults 18 and over—and 11% of those 18-24—vaped, and white adults (5.2%) were more likely to vape than Hispanic (3.3%), Black (2.4%) or Asian (2.9%) adults, according to the National Center for Health Statistics.

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