Kaleo Inc has discontinued its naloxone hydrochloride injection product Evzio and its authorized generic, according to Optum Healthcare and Mitchell.com. In addition, the FDA Orange Book lists that the product is discontinued.

Evzio was approved by the FDA in April 2014 for the emergency treatment of known or suspected opioid overdose, as manifested by respiratory and/or central nervous system depression.

Kaleo released a generic Evzio in December 2018.