Eucapnic voluntary hyperventilation (EVH) could not be used interchangeably with treadmill running to diagnose exercise-induced bronchoconstriction in children with asthma, according to study results reported by

“Although simple, safe and with a good positive predictive value, eucapnic voluntary hyperventilation cannot be used interchangeably with exercise as a diagnostic bronchial provocation for exercise-induced bronchospasm,” study researcher José Â. Rizzo, MD, PhD, director of education, research and extension at the Clinical Hospital of Federal University of Pernambuco in Brazil, told

Rizzo and colleagues conducted a cross-sectional study to assess the differences between EVH and treadmill running in diagnosing exercise-induced bronchoconstriction (EIB) in children with asthma. The cohort included 34 children aged 8 to 18 years who attended the allergy clinic at Federal University of Pernambuco from September to December 2013.

Nineteen patients responded positively after treadmill running, and 17 had a positive response after EVH. FEV1 appeared to decrease in six patients after treadmill running and in four after EVH.