This article was originally published on April 30, 2025. Additional updates will be made as new data is available.
US Mumps Cases Reach 332
Dec 22, 2025
As of December 4, 2025, a total of 332 mumps cases have been reported in 36 states and New York City, according to an update by the CDC.

As of December 4, 2025, the following jurisdictions have reported cases:
| Number of Cases | State/Jurisdiction |
|---|---|
| 49 cases | California |
| 24 cases | New York City |
| 22 | IL |
| 20 | CO, FL |
| 19 | MI, VA |
| 18 | OH |
| 16 | KY |
| 10 | TN, WA |
| 9 | MD |
| 8 | IA, WI |
| 7 | MA, NJ, NC, PA |
| 6 | UT |
| 5 | IN |
| 4 | AZ, HI, KS, LA, OK |
| 3 | GA, MN |
| 2 | AL, ID, NE, OR, WV |
| 1 | MS, MT, NY, SC, VT |
Mumps cases have not exceeded 2024 totals (400 cases reported). The fewest cases reported in a single year occurred in 2021, with only 189 cases. The highest case count in the last quarter century was 2006, when 6,584 cases were reported in the United States.
The CDC recommends vaccination as the best prevention strategy, encouraging all Americans to be vaccinated via two doses of the mumps vaccine (measles, mumps, and rubella [MMR] vaccine).

US Mumps Cases Now at 226
Sept 15, 2025
A total of 226 mumps cases have been documented in 33 states and New York City, according to a Sept 11 update by the Centers for Disease Control and Prevention.
As of As of September 11, 2025, the following jurisdictions have reported cases:
| Number of Cases | State/Jurisdiction |
|---|---|
| 29 cases | California |
| 20 cases | New York City |
| 19 | IL, MI |
| 16 | OH |
| 12 | FL |
| 10 | WA |
| 9 | VA |
| 8 | CO, IA |
| 7 | KY, NJ, WI |
| 6 | MD, MA, NC, TN |
| 3 | AZ, IN, KS, PA, UT |
| 2 | AL, HI, LA, NE |
| 1 | AK, GA, ID, NH, NY, SC, VT, WV |
Mumps cases have not exceeded 2024 totals (400 cases reported). The fewest cases reported in a single year occurred in 2021, with only 189 cases. The highest case count in the last quarter century was 2006, when 6,584 cases were reported in the United States.
The CDC recommends vaccination as the best prevention strategy, encouraging all Americans to be vaccinated via two doses of the mumps vaccine (measles, mumps, and rubella [MMR] vaccine).
US Mumps Cases Cross 100
April 30, 2025
A total of 106 mumps cases have been documented in 24 states and New York City, according to an update by the Centers for Disease Control and Prevention.
As of As of April 24, 2025, the following jurisdictions have reported cases:
| Number of Cases | State/Jurisdiction |
|---|---|
| 11 cases | California |
| 10 cases | MI, OH, New York City |
| 9 | IL |
| 8 | FL |
| 6 | WI |
| 5 | ME, VA |
| 4 | IA, MD |
| 3 | NJ, TN |
| 2 | AZ, CO, IN, KY, PA, UT |
| 1 | AK, ID, KS, MS, NH, NY |
Comparatively, mumps cases are at their lowest number in the last 25 years, according to CDC data. In 2024, a total of 357 cases were reported. The fewest cases reported in a single year occurred in 2021, with only 189 cases. The highest case count in the last quarter century was 2006, when 6,584 cases were reported in the United States.