According to a study presented at the 47th Annual Meeting of the American Association for Dental Research, mice embryos exposed to e-cigarette vapor (aerosol mixtures) developed craniofacial abnomalities in vivo. The findings also report that flavored e-cig vapor showed greater detrimental effects than non-flavored vapor in all treatment.

This study aimed to determine the effects of e-cig aerosol mixtures (e-cigAM) on shape changes of craniofacial structures in developing murine embryos in vivo.

“In vivo exposure to e-cigAM during pregnancy decreased embryo number,” said Suraj Kandalam.” E-cigAM exposure also generated shape changes including narrowing and shortening of the orofacial area in RG and flavored e-cigAMs. “Significant differences in distance between the mandible and premaxilla and of the occipital bone in both research grade with and without nicotine were observed compared to control.