Aclidinium bromide can improve exercise endurance, physical activity, and exertional dyspnea in COPD  patients.

“The results of this study show that after 3 weeks, aclidinium 400 mcg twice daily significantly reduced the intensity of exertional dyspnea and improved cycling exercise endurance compared with placebo,” the researchers wrote.

Researchers administered a randomized, double blind, crossover study from November 2011 to June 2012 at 14 locations in Germany, Spain and the United Kingdom. Eligible participants were aged 40 years or older and had moderate-to-severe COPD, along with being current or former cigarette smokers. Participants with a history of asthma or any other respiratory or cardiovascular condition were excluded from the study.

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