Researchers say they have developed a vaccine that they say could reduce the number of deaths from opioid overdose.

In the journal ACS Chemical Biology, scientists from The Scripps Research Institute (TSRI) in La Jolla, CA, describe how the vaccine stopped two opioids – oxycodone and hydrocodone – from reaching the brains of mice, reducing symptoms of a drug “high.”

What’s more, the vaccine appeared to reduce the toxic effects of opioids in the mice.

If these results translate to humans, the researchers say the vaccine has the potential to reduce the risk of death from opioid overdose.