Macrophages are a type of white blood cell that engulf and digest cellular debris and foreign substances. They play a substantial role in stimulating the body’s immune system and help to promote healthy inflammation.

However, once the time has come for the inflammation response to stop, they switch roles, suppressing inflammation and busying themselves with repairing damaged tissue.

According to a study published in Cell, during inflammation, macrophages were found to halt mitochondria’s production of energy and switch them to producing toxic compounds that further amplify inflammation.