Masimo Corp, Irvine, Calif, has announced the approval of its PVI measurement by the Japanese Ministry of Health, Labor and Welfare (MHLW).

PVI is a dynamic new indicator of fluid responsiveness that does not require an invasive procedure or manual calculation.

PVI is an index that has been demonstrated as an accurate predictor of fluid responsiveness in mechanically ventilated patients. The index is automatically derived from the Masimo plethysmographic waveform. PVI is designed to help clinicians detect when a patient’s cardiac function is compromised.

A numerical Masimo PVI value is continuously displayed on Masimo Rainbow SET Pulse CO-Oximeters, which may help to determine if a patient is dehydrated or over-hydrated.

Identification and rapid intervention of patients most likely to respond to fluid administration during surgery and post-operatively can facilitate organ preservation.

Clinical studies have shown that current static methods for assessing fluid responsiveness are poor predictors of fluid responsiveness. Dynamic indices, such as respiratory variations in arterial pulse pressure, inferior vena cava diameter, superior vena cava diameter and stroke volume, present significant limitations, are invasive and often operator-dependent.