Category: Chronic Pulmonary Disorders

Chronic Pulmonary Disorders

FDA Expands Casgevy for Children 2+ with Sickle Cell Disease

The FDA approved the first gene therapy for children as young as 2 years old with sickle cell disease or transfusion-dependent beta thalassemia.

Chronic Pulmonary Disorders

Asthma Attacks May Permanently Alter Airway Tissues

Research using lung-on-a-chip technology shows that mechanical stress from asthma attacks causes tissue damage independently of inflammation.

Chronic Pulmonary Disorders

Hidden Inflammation in Primary Ciliary Dyskinesia

Testing via oral swabs identified hidden systemic inflammation in patients with primary ciliary dyskinesia even when they were not experiencing acute illness.

Asthma

Racial, Ethnic Disparities Persist in Asthma Inhaler Use

A study of over 1.1 million American adults with asthma found that Black, Hispanic, and Asian patients use ICS, LABA and LAMA inhalers less frequently than white patients.

COPD

Nebulized Dual Bronchodilator Aero-007 Improved COPD Lung Function

AERO-007 demonstrated significant lung function improvements over 24 hours in patients with moderate-to-severe COPD.

Cystic fibrosis

Cystic Fibrosis Patient Receives Quadruple Transplant

A 28-year-old cystic fibrosis patient underwent a 36-hour quadruple organ transplant for both lungs, a liver, and a kidney from a single donor.

Pulmonary Fibrosis

Nebulized Treprostinil Preserved IPF Lung Function

Phase 3 trial results show significant reductions in clinical worsening and acute exacerbations for patients with idiopathic pulmonary fibrosis (IPF).

Allergies

Fatal Pediatric Anaphylaxis Linked to Delays in Epinephrine Treatment

New studies suggest that airway and breathing failures are the primary causes of death in childhood food anaphylaxis, requiring a shift in emergency management protocols.

Other Chronic Diseases

Inhaled Molgramostim Improved Exercise Capacity

Phase 3 clinical trial data shows improvements in walking distance and duration for patients with autoimmune pulmonary alveolar proteinosis treated with inhaled molgramostim.