Excessive nerves in the airways due to remodeling are a key contributor to heightened sensitivity and airway constriction in patients with asthma, according to a study in Science Translational Medicine.

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To study airway nerves in asthma, researchers used OHSU’s state-of-the-art confocal microscopes to generate three-dimensional imagery capturing a complete picture of airway nerves and their interactions with eosinophils.

Using this new 3-D method, [researchers] studied the length of nerves and how often they branch in the airways of healthy patients and in patients with asthma. They found that in asthma, airway nerves are denser.

Read more at www.sciencedaily.com