Research Brief: Signal Transduction and Targeted Therapy
Researchers tracing the origins of research into the lung microbiome recommend greater analysis and study, according to a retrospective review of research published in Nature: Signal Transduction and Targeted Therapy.1
Scientists publish a summary of research into the lung microbiome’s history, composition, and function, noting that it remains incompletely characterized. “…we still need to address the shortcomings of this research area,” they write.1
The review covers the composition of a healthy lung microbiome, which they say “is transient and is influenced by adjacent body parts and the external environment,” namely the oropharynx and gut microbiome.1
They also noted that the lung bacteriome has been intensively studied but relatively little research has focused on the mycobiome and virome. Scientists also detail the role the pulmonary microbiome plays in the innate and adaptive immune responses, and diseases like asthma and COPD.1
Read the review at www.nature.com
- Li R, et al. Lung microbiome: new insights into the pathogenesis of respiratory diseases. Sig Transduct Target Ther 9, 19 (2024). https://doi.org/10.1038/s41392-023-01722-y
