A two-year-old Indiana child is the first in the United States to be diagnosed with Rajab Interstitial Lung Disease with brain calcifications (RILDBC-1), a rare genetic disease with only 10 known cases worldwide, according to a local Indiana news report.
Rajab ILD BC-1 normally presents in infancy or early childhood with poor growth and interstitial lung disease, with some patients experiencing liver, skeletal, and renal abnormalities, and intracranial calcifications on brain imaging.
According to 14 News (Evansville, Indiana), two-year-old Wrenley Lantaff was diagnosed with Rajab in October 2025 and is currently experiencing liver failure and awaiting a liver transplant.
Wrenley’s family is hosting a fundraiser on July 18 to cover the toddler’s transplant-related medical expenses. More information on their fundraising is available on the Children’s Organ Transplant Association website.
