FDA Approves Updated COVID Vaccines from Pfizer and Moderna
The mRNA vaccines are formulated to more closely target currently circulating variants by including a monovalent component that corresponds to the Omicron variant XBB.1.5.
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FDA Approves Updated COVID Vaccines from Pfizer and Moderna
The mRNA vaccines are formulated to more closely target currently circulating variants by including a monovalent component that corresponds to the Omicron variant XBB.1.5.
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Omicron Subvariant BA.5 Mutation Could Efficiently Infect Lung Cells
Researchers have identified a mutation in the spike protein of the Omicron subvariant BA.5 that enables the virus to efficiently infect lung cells again.
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Long COVID More Common in Those Infected pre-Omicron
Long COVID was more common and severe in study participants infected before the 2021 Omicron variant, according to initial findings from a study of nearly 10,000 Americans.
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mRNA Booster May Be Less Effective if Previously Infected
Additional protection offered by the initial COVID booster shot may be reduced among people with a previous COVID-19 infection, according to a study published in Plos Medicine.
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Moderna Submits Omicron-targeting Bivalent Booster Vaccine to FDA
Moderna Inc has completed its submission to the FDA for emergency use authorization for its BA.4/BA.5 Omicron-targeting bivalent booster vaccine, mRNA-1273.222.
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Omicron Less Severe Than Delta for Children Under 5
Children younger than age 5 who are infected with the COVID-19 Omicron variant have less risk of severe health outcomes than those infected with the Delta variant, according to research published in JAMA Pediatrics.
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Monoclonal Antibody Sotrovimab No Longer Authorized in Northeastern US
The FDA revoked the emergency use authorization for the monoclonal antibody Sotrovimab in the Northeastern US due to its ineffectiveness against the Omicron BA.2 subvariant.
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Cases of Stealth Omicron Subvariant BA.2 Are Increasing
BA.2, a novel subvariant of the Omicron strain of the SARS-CoV-2 virus, is stoking fears of a new wave of COVID-19 infections in the US and internationally.
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Scientists Unveil Molecular Analysis of Omicron Spike Protein
The analysis—done at near-atomic resolution using cryo-electron microscopy—reveals how the heavily mutated Omicron variant attaches to and infects human cells.
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Omicron More Transmissible But Less Severe
The latest numbers show that new daily COVID-19 hospitalizations and excess deaths have been lower than the rate of increase in new COVID-19 cases, suggesting that the variant may cause less severe illness.
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